Symposium “Signaling Through Chromatin”
Monday November 25th. Grenoble, Maison Minatec.
Session 1. Chromatin and Signaling: an integrative platform
Keynote by Geneviève Almouzni (Institut Curie, Paris)
Chromatin assembly and histone chaperones.
Valérie Borde (Institut Curie, Paris)
Histone H3K4 methylation and meiotic recombination hotspots
Robert Schneider (IGMBC, Strasbourg)
Novel modifications – novel players in chromatin function
Johanna Samuelsson (Active Motif, California).
FFPE-ChIP-seq reveals the clinical importance of histone marks and their relation to DNA methylation in long-term stored FFPE colon cancer samples.
Emilie Montellier (Institut Albert Bonniot, Grenoble).
Chromatin-to-nucleoprotamine transition is controlled by the histone variant TH2B during spermatogenesis
Session 2. Proteomics and chromatin signaling
Mihaela Sardiu (Washburn lab, Stowers Institute, Kansas, USA).
A Proteomics approach for understanding protein networks underlining chromatin remodeling complexes
Michiel Vermeulen (Utrecht, Netherlands).
Reading the epigenome: developmental and evolutionary dynamics of 5-(hydroxy) methylcytosine readers in vertebrates
Cyril Boyault (Institut Albert Bonniot, Grenoble).
Understanding the protein network involved in heterochromatin formation by quantitative proteomics
Eric Trinquet (CisBio)
A new HTRF platform to investigate epigenetic targets
Session 3. Chromatin signaling deciphered by structural biology
Keynote by Andreas Ladurner (University of Munich).
The chaperone FACT in complex with H2A-H2B and new tools for cell-type-specific genomics
Daniel Panne (EMBL, Grenoble).
Structure of the p300 catalytic core and implications for HAT regulation and chromatin targeting
Alessandro Tosi (University of Munich).
Structure and subunit topology of the INO80 chromatin remodeler and its interaction with the nucleosome
17:30 Closing remarks